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genetics

Infographic showing the breeding schematic to generate Cre-loxP tissue-specific knockout mice.
Infographic: The Cre-lox System Explained
Laura Tran, PhD | Dec 4, 2023 | 1 min read
The Cre-lox recombination method orchestrates remarkable genetic manipulations that remain a gold standard for transgenic mice.
Eytan Stibbe wears a headset and a blue shirt while surrounded by computers and other equipment on the International Space Station.
Whenever, Wherever: Taking DNA Amplification Outside the Lab
Hannah Thomasy, PhD | Dec 4, 2023 | 10 min read
Recombinase polymerase amplification lets researchers rapidly replicate DNA in the clinic, in the field, or even in the International Space Station.
Comprehensive Quality Control and Interactive Analysis of Single Cell RNA-seq Data
Comprehensive Quality Control and Interactive Analysis of Single Cell RNA-seq Data
The Scientist | 1 min read
In this webinar, Joshua Campbell will talk about the fundamentals of scRNA-seq analysis and how to handle various challenges. 
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Samantha Maragh speaks on stage after receiving the State of Maryland Outstanding Young Scientist Award 2019.
Making Standards Exceptional
Meenakshi Prabhune, PhD | Dec 4, 2023 | 9 min read
Samantha Maragh has taken on the difficult challenge of standardizing assays, data norms, and terminology in the ever evolving genome editing field.
Saliva DNA collection kit.
From Sample to Insight: Leveraging Total Nucleic Acids in Genomics and Microbiome Research
DNA Genotek Inc. | 1 min read
Learn about the research advantages of a saliva sample collection device that standardizes at-home collection.
Naked mole rat
Fighting Cancer: Lessons from the Naked Mole-rat
Hannah Thomasy, PhD | Dec 1, 2023 | 2 min read
Mice live longer, healthier lives thanks to a gene from their glabrous subterranean cousins.
Rodents Offer New Insights Into the Diversity of Addiction
Aparna Nathan, PhD | Dec 1, 2023 | 4 min read
Molecular studies may point to underlying genetics and therapeutic targets.
A semi-automated liquid handling robot with a multi-channel attachment for pipetting samples into an array format.
The Latest in Lab Automation
Deanna MacNeil, PhD | 5 min read
As technologies advance, laboratory automation becomes reachable for researchers seeking high throughput approaches and reproducible results.
Photographic rendering of Woolly Mammoth and elephant with background elements merging together
Measuring Mammoth Mutations
Hannah Thomasy, PhD | Dec 1, 2023 | 2 min read
Comparing mammoth and elephant genomes revealed genetic mutations that may have helped mammoths survive in the Arctic.
Epigenetic Changes Drive Cancer 
Rebecca Roberts, PhD | Nov 28, 2023 | 3 min read
An analysis of almost 700 different tumors revealed that DNA methylation drives tumorigenesis just like genetic mutations do. 
New Strategies to Discover Human Disease Genes
New Strategies to Discover Human Disease Genes
The Scientist | 2 min read
Learn how researchers across health-related fields identify and characterize disease-causing genomic variants.
A field of yellow sunflowers in front of a blue sky.
Chasing the Sun
Aparna Nathan, PhD | Nov 14, 2023 | 3 min read
Sunflowers may use a complex set of molecules to track the sun in the sky.
A vial labeled “mRNA vaccine” and a syringe on a blue background.
An Updated Approach to mRNA Vaccine Quality Assessment
Deanna MacNeil, PhD | Nov 13, 2023 | 3 min read
Researchers developed and validated a sequencing method for mRNA vaccines, moving the manufacturing field forward by linking established technologies with translational applications.
<em >The Scientist</em>&rsquo;s Journal Club: Detecting Nucleic Acids with CRISPR
The Scientist’s Journal Club: Detecting Nucleic Acids with CRISPR
The Scientist | 1 min read
Kuangwen Hsieh will discuss his research understanding CRISPR-based nucleic acid detection assays.
The Wonderfully Shrunken Cas13
Rachael Moeller Gorman | Nov 7, 2023 | 3 min read
Scientists removed unnecessary sections of the Cas13 enzyme, creating a mini-enzyme that works and fits with other CRISPR elements into a single gene therapy vector.
A blue gloved hand holding a long, brown cotton swab with a dirty tip.&nbsp;
A Menagerie on a Leaf
Rachael Moeller Gorman | Nov 6, 2023 | 4 min read
A simple rainforest leaf swab revealed DNA from dozens of animal species, possibly improving biodiversity monitoring in the future.
PCR tubes placed into the 96-well loading chamber of a PCR thermocycler instrument.
Directing Superior Reagents for Better PCR Results
The Scientist and MilliporeSigma | 3 min read
Directed evolution approaches are creating new reagents to help a tried-and-true technique reach new heights.
Image of cochlear implant and hearing aid.
Reversing Hearing Loss
Laura Tran, PhD | Nov 1, 2023 | 2 min read
Gene reactivation restored hearing after loss in mice, but the timing of intervention is key.
Genome sequence map concept
Mind the Genome Gap
Mariella Bodemeier Loayza Careaga, PhD | Nov 1, 2023 | 2 min read
Population geneticist Tábita Hünemeier seeks out isolated indigenous groups living in the Brazilian Amazon rainforest to expand understanding of the human genome.
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