cell biology

Not all degenerated intervertebral discs are painful; a new study identified a subset of disc cells that triggers a pathway to pain.

A protein’s timely appearance is crucial for Toxoplasma gondii’s unique replication cycle.

Pregnancy hormones help mice prepare to take care of their young by altering activity in neurons.

Colby Duncan uses a powerful criminal justice tool to decode DNA evidence.

A common mistake and a well intentioned but misguided gesture led Allison Mackay’s experiment awry in the lab.

Benchtop analytics get a boost from automated single cell dispensing technology that combines microfluidics, flow cytometry, and liquid dispensing.

Scientists identified neurons that drive the disagreeable symptoms of motion sickness in mice.

Transgenic ferret models ratted out how a rare cell type affects airway function.

A whole-body immunostaining method allowed researchers to achieve cellular resolution at the whole-organism level.

Researchers developed a “test tube” so tiny that it can hold a single cell. These vials enabled them to connect protein secretion levels with surface markers and transcriptome data from the same cell. 

A 3D variation of pooled CRISPR screens could connect the dots between autism spectrum disorder genetics and cell fate pathways in the developing brain.

Dietary changes rapidly alter T cell metabolism, but the effects can be reversed.

Dorothy Shippen and Borja Barbero Barcenilla investigated how spaceflight affects telomeres of Arabidopsis seedlings grown on the International Space Station.

Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice.