CRISPR

Understanding how Cas9 binds off-target sequences can help researchers refine CRISPR-mediated genome editing.

A 3D variation of pooled CRISPR screens could connect the dots between autism spectrum disorder genetics and cell fate pathways in the developing brain.

A risk-benefit analysis of gene editing tools in stem cells revealed that base and prime editing carry vulnerabilities similar to those of CRISPR-Cas9, but at a reduced rate. 

Recombinase polymerase amplification lets researchers rapidly replicate DNA in the clinic, in the field, or even in the International Space Station.

Samantha Maragh has taken on the difficult challenge of standardizing assays, data norms, and terminology in the ever evolving genome editing field.

Scientists removed unnecessary sections of the Cas13 enzyme, creating a mini-enzyme that works and fits with other CRISPR elements into a single gene therapy vector.

Engineered bacteria sound the alarm on a common oncogenic mutation.

Scientists used CRISPR-Cas9 for the first time in a carnivorous plant to prove the role of two ion channels in closing the Venus flytrap’s trap.

Brain-like tissue grown in a dish mimics critical periods for development and reveals how it can go wrong.

In the fight between hosts and fungal pathogens, scientists discovered how withholding manganese can cripple Candida albicans.

Two groups independently discovered that Fanzor proteins in eukaryotic organisms are CRISPR’s genome-editing cousins.

Scientists combine the power of genome-wide screens and machine learning to unlock the secrets of transcriptome engineering with Cas13.

Researchers design dual CRISPR treatments to remove HIV DNA and prevent reinfection in vitro.