Specialized multiplex PCR techniques combined with high-throughput sequencing technology have the power to enumerate and quantify tens of thousands of T and B cell receptor clonotype sequences accurately and reproducibly. Scientists can use this information to characterize variations in immune activation and the distribution of clonotypes across samples and study immune patterns of health and disease. Immune receptor repertoire profiling is an important analytic tool for disease research in many areas, including cancer, autoimmunity, organ transplantation, infectious disease, and more.
Download this poster from Cellecta to learn how to efficiently profile all T and B cell receptor hypervariable clonotypes and get rapid insights into a sample’s adaptive immune landscape.