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physiology

The figure shows two waves made of DNA double helixes representing gene expression changes in the malaria parasite and its human host. These changes reveal a synchronization between parasite and host.
Malaria Parasites Sync with Hosts’ Molecular Rhythms
Mariella Bodemeier Loayza Careaga, PhD | Sep 1, 2023 | 2 min read
Evidence of malaria parasites aligning with their human hosts may pave the way for new antimalarial agents.
The image shows round-shaped glial cells in red and elongated neuronal cells in green surrounding the glial cells.
How Stress Inflames the Gut
Mariella Bodemeier Loayza Careaga, PhD | Sep 1, 2023 | 2 min read
In mice, chronically high levels of stress hormones worsen bowel inflammation.
Learn How the Immune System Can Be Trained to Overcome Food Allergies
Retraining the Immune System Cavalry for Food Allergen Peacekeeping Missions
The Scientist | 1 min read
Explore food allergy immunotherapy for reversing patient symptoms.
The image illustrates the relationship between the brain and gut in humans.
A Novel Tool to Explore the Gut-brain Connection
Anna Napolitano, PhD | Aug 28, 2023 | 3 min read
Scientists used a vibrating capsule to assess people’s gut sensitivities and understand how the brain interprets these signals.  
Image representing states of consciousness
High Time: The Roles of Endogenous Psychedelics
Iris Kulbatski, PhD | Aug 1, 2023 | 2 min read
Steven Barker is on a forty-seven-year-long journey to understand the mind-blowing science of psychedelics.
Peripheral blood mononuclear cells surrounded by red blood cells in circulating blood.
Accelerating Immune Research with Cryopreserved Peripheral Blood Mononuclear Cells
The Scientist and MilliporeSigma | 3 min read
Commerically-available peripheral blood mononuclear cells offer a well-characterized, accessible, and consistent model for immunology and therapeutic development.
The image shows a brain section of the mouse amygdala. Using fluorescent markers, the expression of synapses is shown in purple, while neurons are shown as red dots and the microRNA miR-483-5p is shown as green dots.
A Brain MicroRNA Curbs Anxiety
Mariella Bodemeier Loayza Careaga, PhD | Aug 1, 2023 | 2 min read
Upregulation of a specific microRNA in the brain lessened anxiety and reduced the expression of stress-related genes in mice. 
Close-up of women’s hands using lancet on finger.
A Noninvasive Glucose Monitor for Managing Diabetes
Natalia Mesa, PhD | Jul 20, 2023 | 3 min read
A new, invisible fluorescent patch continuously monitors blood glucose levels in mice.
A Scientific Figure of Speech
Science Philosophy in a Flash - A Scientific Figure of Speech
Iris Kulbatski, PhD | 1 min read
Beate Peter shares how her “scientific bilingualism” is the driving force behind her philosophy of science.
Old brown dog with gray on its face and neck
Aging Dogs Provide Insights for Human Longevity
Hannah Thomasy, PhD, Drug Discovery News | Jul 19, 2023 | 6 min read
Biogerontologist Matt Kaeberlein studies aging pets to determine how to improve healthspan in dogs and their humans.
Patient with skin blisters being swabbed by gloved hand
Delivering Gene Therapies in Utero 
Natalia Mesa, PhD | Jul 18, 2023 | 3 min read
By delivering mRNA to the skin of mice in utero, researchers showed a proof-of-concept for shuttling gene therapies to skin cells before birth.
Exosomes, microvesicles, and apoptotic bodies: The three major types of extracellular vesicle.
Extracellular Vesicles: Applications and Potential
Beckman Coulter Life Sciences | 1 min read
Explore why extracellular vesicles are attractive candidates for new therapeutic approaches.
Mouse running on wheel
An Exercise-induced Liver Enzyme Boosts Metabolism
Natalia Mesa, PhD | Jul 7, 2023 | 3 min read
Exercise drives the liver to produce the CES2 enzyme, which circulates in blood and delivers some of the benefits of exercise in mice. 
A fluorescence microscopy image of placenta tissue made up of cells dyed blue, purple, pink and green on a black background.
The Cellular Intricacies of the Human Placenta
Ida Emilie Steinmark, PhD | Jul 5, 2023 | 2 min read
Rare samples saved 35 years ago helped researchers map gene expression and cell differentiation in first trimester placentas.
Developing Aptamer Biosensor Technology for Diagnostics and Therapeutics
Expanding the Available Target Range for New Drugs and Diagnostics with Aptamers
The Scientist and aptamer Group | 1 min read
In this roundtable discussion, an expert panel will discuss how the latest applications of aptamer technology are enabling innovation across the life sciences by replacing antibodies.
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
EKG readout
The Circadian Rhythm of the Heart Rate
Katherine Paulin, PhD | May 31, 2023 | 3 min read
The sympathetic nervous system influences gene expression in the heart to regulate the day-night cycle of resting heart rate.
Large-Scale Proteomics Drives Disease Research
Driving Disease Research and Therapeutics with Large-Scale Proteomics
The Scientist and SomaLogic | 1 min read
Explore how technology enables large-scale proteomics for biomarker discovery and clinical application.
Side and front view of a male human skull
Mechanical Force on the Skull May Aid Bone Regeneration
Alejandra Manjarrez, PhD | May 1, 2023 | 3 min read
By mechanically inducing the expansion of cranial sutures in young adult mice, researchers stimulated stem cell proliferation that is key to healing bone injuries.
Green and brown illustration of cancer cells in front of a peach and yellow background.
Bacterial Tractor Beams Bring Radiation to Tumors
Rachael Moeller Gorman | Apr 17, 2023 | 3 min read
Colonizing tumors with engineered bacteria may allow researchers to target sites currently inaccessible to radionuclide therapy.
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