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biochemistry

Andrew Chapman | Nov 17, 2023 | 3 min read

Melting a bacteriophage’s coat of proteins turns it into a tiny power plant, which could fire up the discovery of new bioengineered devices.

Orange bacteria on a green and orange background.

Bacterial Time Capsules May Inform Future Medicines

Danielle Gerhard, PhD | Nov 1, 2023 | 2 min read

Historical samples of bloodstream infections hold secrets to Escherichia coli’s evolutionary history and the emergence of virulent clones.

A woman with diabetes checks her blood glucose levels using a wearable biosensor patch on her upper arm, transmitting the results to a smartphone.

Wearable Biosensors and Their Applications

Rebecca Roberts, PhD | 5 min read

Allowing users to continually monitor biological signals over time, wearable biosensors pave the way toward personalized healthcare.

A female scientist holds up a burning funnel.

A Ticking Firebomb

Laura Tran, PhD | Nov 1, 2023 | 2 min read

Annalise Rogalsky finally got the potassium metal to react, but not during her experiment.

Line drawings of Moungi Bawendi (left), Louis Brus (center), and Alexei Ekimov (right) from the shoulders up.

Nobel Prize in Chemistry for Quantum Dots

Hannah Thomasy, PhD | Oct 4, 2023 | 3 min read

Moungi Bawendi, Louis Brus, and Alexei Ekimov were awarded the Nobel Prize for their work on quantum dots, which has applications in electronics and biomedicine.

Best Practices for Analyzing Single Cell Proteomics Using Mass Spectrometry

Best Practices for Single-Cell Proteomics Using Mass Spectrometry

The Scientist | 1 min read

In this webinar, Runsheng Zheng and Fernanda Salvato will discuss how to optimally examine single-cell proteomes through label-free, data-independent acquisition (DIA) mass spectrometry.

Black and gold sketch of the three prize winners.

Nobel Prize for Experiments With Light

Danielle Gerhard, PhD | Oct 3, 2023 | 4 min read

Anne L’Huillier, Pierre Agostini, and Ferenc Krausz received this year’s Physics award for creating tools for studying the world of electrons, with future applications in medical diagnostics.

Black and gold sketch of Katalin Karikó and Drew Weissman.

Nobel Prize for mRNA Vaccines

Danielle Gerhard, PhD | Oct 2, 2023 | 5 min read

Katalin Karikó and Drew Weissman received this year’s Physiology or Medicine award for their work on RNA biology and mRNA-based vaccines.

Discover how a cellphone-driven UV gel documentation system accelerates accessible imaging.

Accessible Gel Imaging with a Cellphone

Analytik Jena | 1 min read

In the classroom or the laboratory, a new gel documentation system enables scientists to capture snapshots of their samples in real time.

Illustration of virus with needle puncturing membrane

Designer Peptoids Pop Viral Membranes

Laura Tran, PhD | Oct 2, 2023 | 2 min read

Bioinspired small molecules combat viral threats by targeting a common feature in enveloped viruses, making them useful against a wide range of viruses.

Lipofuscin autofluorescence was quenched using TrueBlack®, allowing effective visualization of glial cells (GFAP antibody stain, cyan) and cell nuclei (magenta) in human cerebral cortex cryosections.

Stepping Out of the Background

The Scientist Staff | Oct 2, 2023 | 1 min read

New innovations for reducing nonspecific fluorescence offer researchers clearer pictures and more multiplexing possibilities.

A photo of a scientist working with an EpMotion® liquid handler.

Simplifying Liquid Handling Workflows with Automation

The Scientist and Eppendorf | 3 min read

Learn about the legacy of liquid handling in molecular breakthroughs and how effortless automation enables more accurate and precise research processes.

: Aerial view of a scattered pile of audio cassette tapes.

Regulating Insulin With Queen’s Greatest Hits

Kamal Nahas, PhD | Oct 2, 2023 | 4 min read

Pop music balanced blood sugar levels in mice, thanks to implanted human cells rigged to release insulin using a sound-sensitive bacterial protein.

Lasker Award winner Piet Borst sits at his desk.

A Journey With Metabolism, Parasites, and Cancer

Laura Tran, PhD | Sep 21, 2023 | 7 min read

Piet Borst led stellar work on cell organelles, trypanosomes, and cancer drug resistance during the golden age of biology.

A 3D rendering of an albumin’s protein structure.

Providing Stability In Vivo, In Vitro, and In Culture

The Scientist and MilliporeSigma | 3 min read

Albumins enable researchers to bind, sequester, and stabilize important molecules across research applications.

Lasker Award for Revolutionizing Protein Structure Predictions

Laura Tran, PhD | Sep 21, 2023 | 6 min read

John Jumper and Demis Hassabis received this year’s 2023 Albert Lasker Basic Medical Research Award for their work on the artificial intelligence system AlphaFold, which changed the landscape of protein biology.