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Rendering of Escherichia coli in blue and purple.
Bugs as Drugs to Boost Cancer Therapy
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
Bugs as Drugs to Boost Cancer Therapy
Bugs as Drugs to Boost Cancer Therapy

Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.

Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.

synthetic biology

Biosensors for Colorectal Cancer
Hannah Thomasy, PhD | Nov 1, 2023 | 4 min read
Engineered bacteria sound the alarm on a common oncogenic mutation.
Glowing red DNA on bluish background
Redesigning Medicine Using Synthetic Biology
Alison Halliday, PhD, Technology Networks | Jun 21, 2023 | 5 min read
Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.
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The Art and Science of Synthetic Biology 
The Scientist | 2 min read
Researchers get creative using bacterial bits and pieces to produce synthetic cells for studying cancer.
Artist&rsquo;s rendering of bright orange <em >E. coli&nbsp;</em>bacteria
New Synthetic E. coli Is Immune to Bacteriophage Infection
Anna Napolitano, PhD | Mar 30, 2023 | 3 min read
Self-contained synthetic E. coli resistant to viral infection could prove invaluable to the biotechnology industry by increasing product consistency and reducing safety concerns. 
A robotic hand adding a piece of DNA to an existing DNA strand to complete the sequence.
A New Way to Control Stem Cell Fate Using Gene Circuits
Elina Kadriu | Feb 27, 2023 | 3 min read
Scientists engineered human pluripotent stem cells with synthetic gene circuits to control differentiation without human input.
Advancing Drug Discovery by Employing Synthetic Biology Tools
Advancing Drug Discovery by Employing Synthetic Biology Tools
The Scientist | 1 min read
In this webinar, learn about the origins of artificial gene circuits and how researchers currently use synthetic biology strategies to uncover new drugs. 
Researchers engineer a protease-mediated post-translational path faster than gene switches for processes that need to happen quickly, such as insulin release.
Post-Translational Control: The Next Step in Synthetic Circuits
Deanna MacNeil, PhD | Feb 27, 2023 | 3 min read
Researchers engineer a protease-mediated post-translational path faster than gene switches for processes that need to happen quickly, such as insulin release.
illustration of T cell attached to protein
“Smarter” CAR T Cells Target Tumors with Precision
Natalia Mesa, PhD | Dec 16, 2022 | 5 min read
Two studies in mice now show that researchers can control when and where CAR T cells are active, potentially overcoming previous hurdles for CAR T–based treatments.
Building Bridges podcast logo
Building Bridges for Translational Research - A Special Podcast Series
The Scientist and Cytiva | 2 min read
Translational scientists discuss their experiences taking preclinical concepts to the market.
Lock and key illustration
Novel Yeast-Assembly Technique Yields Living Materials
Natalia Mesa, PhD | Nov 23, 2022 | 3 min read
Researchers say structures made of the cells could potentially be used to clean up uranium from oceans, heal wounds, and more.
Tree with many scattered branches.
Scientists Resurrect Ancient Rubiscos to Understand Their Evolution
Alejandra Manjarrez, PhD | Oct 14, 2022 | 5 min read
A team proposes that the addition of a small accessory subunit to the carbon-fixing enzyme was key to improving its catalytic properties and specificity to CO2.
Brush Up: Quorum Sensing in Bacteria and Beyond
Brush Up: Quorum Sensing in Bacteria and Beyond
Deanna MacNeil, PhD | 4 min read
Microbes communicate with quorum sensing to coordinate their behavior in response to how many neighbors they have.
Arthur Riggs smiles for the camera
Geneticist Arthur Riggs Dies at 82
Lisa Winter | Apr 14, 2022 | 2 min read
His research paved the way for the development of synthetic insulin to treat diabetes.
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Engineered Yeast Robots Destroy Inflammatory Molecules in an IBD Mouse Model
Roni Dengler, PhD | Aug 16, 2021 | 3 min read
Scientists added a gene circuit that senses and neutralizes proinflammatory ATP to yeast, taking another step towards precision medicine.
Learn How Cutting-Edge Science is Breaking Through Industry Barriers
Focus on Innovation: Scientific Advances Driving Biopharma Market Trends
The Scientist and Tecan | 1 min read
Explore the future of biopharma research and development.
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Could a Synthetic Probiotic Replace a Strict Diet for Patients with Phenylketonuria?
Roni Dengler, PhD | Aug 16, 2021 | 2 min read
Synthetic biologists introduced an engineered microbe that may lead to new treatment options for phenylketonuria.
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A New COVID-19 Spit Test Is as Easy as 1-2-3
Roni Dengler, PhD | Aug 16, 2021 | 4 min read
A device smaller than two stacked decks of cards can reliably detect and discriminate between SARS-CoV-2 variants in spit in less than an hour with results that glow.
Building a Synthetic Biology Platform for Drug Delivery
Building a Synthetic Biology Platform for Drug Delivery
The Scientist | 1 min read
Kate Adamala and Niren Murthy will discuss the latest advances in drug delivery using synthetic biology approaches.
Environmental Cues Keep CAR T Cells on Track
Aparna Nathan, PhD | May 25, 2021 | 4 min read
Pairing CARs with a synthetic receptor makes T cells more lethal tumor killers.
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