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physiology

Bear paw dusted in snow
Hibernating Bears Provide Clue to Preventing Serious Clots in Humans
Natalia Mesa, PhD | Apr 13, 2023 | 3 min read
Low levels of the clotting factor HSP47 protect the sleeping giants from blood clots, and the same may be possible for humans and other mammals.
Conceptual image of doctors and scientists analyzing and treating skin, with an emphasis on the hair follicle and skin layers.
Getting to the Root of Skin Healing
Iris Kulbatski, PhD | Apr 11, 2023 | 4 min read
The intimate link between hair follicles and wound healing is more than skin deep.
Enzymes Cutting Extracellular Matrix
An Introduction to Enzymes
The Scientist | 1 min read
Discover how enzymes work and why they're an integral part of scientific laboratories.
Education anatomy and Histological sample Striated (Skeletal) muscle of mammal Tissue under the microscope.
Mechanical Implant Stirs Wasting Muscle Back into Action
Holly Barker, PhD | Apr 3, 2023 | 3 min read
An implantable device stimulates muscle contraction and prevents muscular atrophy in mice.
Illustration showing an experimental device called MAGENTA and how it works
Infographic: Tissue Implant Gets Muscles Moving, Prevents Atrophy
Holly Barker, PhD | Apr 3, 2023 | 1 min read
The experimental device, known as MAGENTA, forces muscles to contract, simulating natural movement. 
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Metabolomic Links Between Environmental Exposures and Human Health
The Scientist | 1 min read
Experts discuss how untargeted metabolomic studies connect environmental factors with human disease.
mouse
hCINAP Protein Key to Cellular Senescence: Study
Patience Asanga | Mar 23, 2023 | 3 min read
The authors claim that by preventing the formation of senescent cells, the protein could delay aging, but experts are skeptical.
Fluorescent image of breast tissue
Hormone Therapy Triggers Male Gene Patterns in Transgender Men’s Cells
Holly Barker, PhD | Mar 15, 2023 | 3 min read
A study deepens the scientific understanding of how androgens influence breast tissue, which may offer clues to treating breast cancer. 
Spatial Biology in Physiology and Pathology
Spatial Biology in Physiology and Pathology
The Scientist | 1 min read
Elana Fertig and Sanjay Srivatsan discuss the importance of the spatial dimension for biological systems research.
White mouse at the edge of a desk
The Heart Can Directly Influence Our Emotions
Natalia Mesa, PhD | Mar 1, 2023 | 4 min read
Researchers find that an increased heart rate can induce anxiety in mice, given the right context.
<em>We are Electric</em> book cover
The Skin Battery
Sally Adee | Mar 1, 2023 | 4 min read
The “wound current” has intrigued scientists for more than a century. It could turn out to be the key to healing catastrophic injuries.
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Demystifying the Black Box
The Scientist and Tecan | 1 min read
One sophisticated laboratory tool detects absorbance, fluorescence, FRET, luminescence, live cells, and more, facilitating a wide variety of experimental findings.
A fingerprint with three sections colored
Finally, Scientists Uncover the Genetic Basis of Fingerprints
James M. Gaines | Feb 23, 2023 | 4 min read
Much like with a zebra’s stripes or a leopard’s spots, Turing patterns explain how the distinctive patterns of human fingerprints form, a study finds.
Artist&#39;s rendering of rod-shaped bacteria
Gut Microbiomes Offer Insights into Chronic Fatigue Syndrome
Shafaq Zia | Feb 21, 2023 | 2 min read
Levels of health-promoting gut bacteria are linked with severity of fatigue symptoms, a study finds.
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Technique Talk: Redefining Mouse Transgenesis with CRISPR-Cas Technology
The Scientist | 1 min read
Learn how CRISPR-Cas technology has revolutionized the creation of transgenic mouse models.
A 3D medical illustration of a human heart with a cardiogram in the foreground and a blue background that includes DNA helices.
Connecting the Complexities of Heart Failure and Aging
Deanna MacNeil, PhD | Feb 13, 2023 | 3 min read
Researchers learned how IGFBP7, a senescence signaling protein and biomarker, promotes cardiac remodeling and cellular aging.
a mouse moves away from the camera, its left leg caught in a cloth
Scientists Discover New “Superfast” Muscle Fibers in Mouse Limbs
Katherine Irving | Feb 9, 2023 | 4 min read
Fast twitch fibers like these could one day be used to treat diseases like Parkinson’s.
Defined Primary Cell Culture and Media
The Scientist Creative Services Team in collaboration with MilliporeSigma | 3 min read
A new partnership opens the door for a source of highly purified human primary cells and defined cell culture media.
The face of a young woman and the face of an old man surrounded by mechanical clocks.
Daily Gene Expression Rhythms Vary with Sex and Age: Study
Alejandra Manjarrez, PhD | Feb 2, 2023 | 3 min read
By studying tissues from deceased people, a team found that women have more rhythmical gene expression and that this molecular rhythmicity decreases with age.
a centrifuge from a birds-eye view, spinning quickly with a colored blur&nbsp;
Scientists Use Centrifuge to Discover a Hormone
Katherine Irving | Jan 23, 2023 | 3 min read
A new method for isolating extracellular fluid aims to discover molecules with therapeutic potential that were previously obscured by highly abundant proteins.
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