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neoantigens

Addressing Power and Pitfalls in Machine Learning Neoantigen Prediction

Deanna MacNeil, PhD | Dec 11, 2023 | 4 min read

Researchers honed prediction models and datasets to unlock the potential of deep neural networks in biological applications while avoiding bias.

Neoantigen Prediction for Precision Immunotherapies

The Scientist | Jan 12, 2023 | 2 min read

Learn about the tools and resources researchers use to define, discover, and deploy anti-tumor immunotherapies.

Can mRNA Vaccine Momentum Propel Tumor Immunotherapies?

Aparna Nathan, PhD | Nov 12, 2021 | 4 min read

A guide to mRNA-based cancer vaccines and where they’re headed next

Cancer-Specific Antigens Encoded in “Junk” DNA

Carolyn Wilke | Apr 1, 2019 | 2 min read

Researchers found that allegedly noncoding genetic material carries the instructions for many peptides that may help harness the immune system to fight cancer.

Personalized Cancer Vaccines Show Promise for Melanoma

Jef Akst | Jul 6, 2017 | 2 min read

In two early trials, vaccines tailored to the mutations in individuals’ cancers appeared to protect 12 of 19 patients against relapse.

Hitting It Out of the Park

Mary Beth Aberlin | Apr 1, 2017 | 3 min read

Cancer can be as evasive and slippery as a spitball, but new immunotherapies are starting to connect.

Contributors

Diana Kwon | Apr 1, 2017 | 3 min read

Meet some of the people featured in the April 2017 issue of The Scientist.

Neoantigens Enable Personalized Cancer Immunotherapy

Stephen P. Schoenberger and Ezra Cohen | Apr 1, 2017 | 9 min read

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

Infographic: Targeting Cancer Antigens

Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017 | 1 min read

Neoantigens may serve as valuable targets for new immunotherapies.