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This shows a cryo-EM map of a Fanzor protein in complex with its guiding RNA (in purple) and DNA (target strand in red, complementary strand in blue).
CRISPR-like Abilities in Eukaryotic Proteins
Two groups independently discovered that Fanzor proteins in eukaryotic organisms are CRISPR’s genome-editing cousins.
CRISPR-like Abilities in Eukaryotic Proteins
CRISPR-like Abilities in Eukaryotic Proteins

Two groups independently discovered that Fanzor proteins in eukaryotic organisms are CRISPR’s genome-editing cousins.

Two groups independently discovered that Fanzor proteins in eukaryotic organisms are CRISPR’s genome-editing cousins.

genome editing

Samantha Maragh speaks on stage after receiving the State of Maryland Outstanding Young Scientist Award 2019.
Making Standards Exceptional
Meenakshi Prabhune, PhD | Dec 4, 2023 | 9 min read
Samantha Maragh has taken on the difficult challenge of standardizing assays, data norms, and terminology in the ever evolving genome editing field.
Medical illustration of a scientist replacing part of a DNA molecule with tweezers, representing genome editing.
On the Hunt for the Next Breakthrough in Motor Neuron Disease
Deanna MacNeil, PhD | May 9, 2023 | 3 min read
Researchers leave no stone unturned in the search for a spinal muscular atrophy treatment strategy that uses base editing.
Conceptual vector illustration depicting CRISPR gene editing by scientists for medical applications.
Optimizing Gene Editing with PARP1 CRISPR Plasmids 
The Scientist and Santa Cruz Biotechnology, Inc. | 3 min read
CRISPR plasmids provide a robust solution for streamlining human cell transfection workflows.   
3D representation of a DNA helix and with a base offset from the main helix, illustrating the concept of base editing.
A CRISPR Alternative for Correcting Mutations That Sensitize Cells to DNA Damage
Deanna MacNeil, PhD | Oct 10, 2022 | 3 min read
Researchers turned to base editors to correct mutations causing the rare genetic disease Fanconi anemia without inducing double-strand DNA breaks.
untitled-design
From Bench to Boardroom
Aparna Nathan, PhD | Oct 25, 2021 | 5 min read
Taking inspiration from her PhD research, Ana Moreno formed a company where scientists use CRISPR to treat chronic pain
David Liu
Targeting a Genetic Accident to Treat Disease
Deanna MacNeil, PhD | 2 min read
David Liu shares how integrating chemistry and evolution in his research has directed his work on base editing techniques aimed at developing new therapeutics.
cartoon depiction of a pair of scissors about to cut a DNA double helix
Researchers Uncover New Families of Gene-Editing Enzymes
Annie Melchor | Sep 15, 2021 | 2 min read
The results reveal evolutionary relatives of the Cas9 enzyme now used extensively in biotechnology.
cartoon showing a hand taking a tool to a double-helix of DNA to represent gene editing
WHO Releases New Recommendations on Human Genome Editing
Annie Melchor | Jul 12, 2021 | 3 min read
The guidance comes after two years of consulting with hundreds of stakeholders, including indigenous peoples, religious leaders, patient groups, and scientists.
Using Genetics and Genomics to Improve Food Security
The Scientist | 1 min read
Pamela Ronald and Kan Wang will discuss how they enhance the yield and disease resistance of important crops.
CRISPR, Cas-9, Nobel, Chemistry
CRISPR’s Adaptation to Genome Editing Earns Chemistry Nobel
Amanda Heidt | Oct 7, 2020 | 4 min read
Emmanuelle Charpentier and Jennifer Doudna reprogrammed the bacterial immune response into one of the most popular tools for genetics and molecular biology.
Panel Lays Out Guidelines for CRISPR-Edited Human Embryos
Lisa Winter | Sep 4, 2020 | 2 min read
The International Commission on the Clinical Use of Human Germline Genome Editing claims the technology is still too risky for therapeutic use.
Laptop displays CRISPR poster.
The Next Generation of CRISPR-Cas Systems
Nathan Ni, PhD | 1 min read
Researchers reinvent genome editing with new CRISPR-Cas systems.
crispr-cas9 duplications off-target effects insertions knock-ins
CRISPR Can Create Unwanted Duplications During Knock-ins
Katarina Zimmer | Feb 19, 2020 | 5 min read
A new study in mice documents frequent undesirable repeats of DNA insertions that are not detected using standard PCR analysis.
Ten Minute Sabbatical
The Scientist | Jan 13, 2020 | 2 min read
Take a break from the bench to puzzle and peruse.
CRISPR Biosensors for Disease Diagnostics
The Scientist | 1 min read
Kiana Aran and Can Dincer will discuss potential advantages and diagnostic applications of CRISPR biosensing.
buri recombinetics hornell cow hereford bull polled genetically engineered talens gmo cattle livestock
Genome-Edited Hornless Cows’ Offspring Are Healthy: Study
Kerry Grens | Oct 9, 2019 | 2 min read
All six calves inherited the gene for preventing horn growth, but four also got a piece of the plasmid used to introduce the sequence to their dad—complicating regulatory approval.
crispr baby he jiankui gene editing genome fertility clinic emails
Fertility Clinics Sought Advice from Scientist Who CRISPRed Babies
Chia-Yi Hou | May 29, 2019 | 1 min read
Emails reveal that a facility in Dubai and others have asked geneticist He Jiankui for help in gene-editing embryos.
CRISPR Technologies for the New Era of Cell and Gene Therapy
The Scientist | 1 min read
Experts will discuss how they use new CRISPR technologies to advance their cell and gene therapy research.
Scientist Forged Ethical Reviews for CRISPRed Babies
Kerry Grens | Jan 21, 2019 | 1 min read
He Jiankui could face charges after an investigation finds he used techniques prohibited in China to edit the genes of twin girls.
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