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Fixing the Problem with Induced Pluripotent Stem Cells
Tanvir Khan, PhD | Oct 31, 2023 | 4 min read
A new strategy prevents reprogramming-induced epigenetic aberrations in human induced pluripotent stem cells.
Unraveling the Mystery of Zombie Genes
Iris Kulbatski, PhD | Oct 31, 2023 | 6 min read
Digging into how and why some genes are resurrected after death sounds morbid, but it has practical applications.
Unlocking the Secrets within Cells Using Next Generation Sequencing
The Scientist | 1 min read
Next generation sequencing (NGS) core facility scientists and researchers discuss their latest work exploring novel cancer models and stem cells in space.
How the Venus Flytrap Captures Its Prey
Rachael Moeller Gorman | Oct 16, 2023 | 4 min read
Scientists used CRISPR-Cas9 for the first time in a carnivorous plant to prove the role of two ion channels in closing the Venus flytrap’s trap.
Which Gene Therapy Delivery Vector Will Emerge Victorious?
Danielle Gerhard, PhD | Oct 2, 2023 | 2 min read
In the race to deliver successful gene therapies, frontrunner AAVs come head to head with underdog lipid nanoparticles.
Smart Gateways into the Lab of the Future
The Scientist | 2 min read
Neurobiologists, computer scientists, and engineers join forces to grow mini brains using automation and make their technologies smarter with artificial intelligence.
Regulating Insulin With Queen’s Greatest Hits
Kamal Nahas, PhD | Oct 2, 2023 | 4 min read
Pop music balanced blood sugar levels in mice, thanks to implanted human cells rigged to release insulin using a sound-sensitive bacterial protein.
The Origins of Hunger Regulation
Mariella Bodemeier Loayza Careaga, PhD | Oct 2, 2023 | 2 min read
A neuropeptide suppressed feeding in two evolutionarily distant species, suggesting that hunger regulation may go back to the roots of the tree of life.
The Scientist's Journal Club: Transcriptomics
The Scientist | 2 min read
Scientists discuss their latest findings on immune cell dynamics, neurodegenerative disease risk factors, and rare cell types obtained from bulk and single cell RNA sequencing experiments.
Silencing Epigenetic Complexes Re-sensitizes Drug-Resistant Cancer Cells
Rachael Moeller Gorman | Sep 25, 2023 | 4 min read
Researchers studying lung cancer cell lines found that chromatin remodeling underlies one type of osimertinib resistance.
The Extra X: How the Sex Chromosome Affects Autoimmunity Risk
Kamal Nahas, PhD | Sep 19, 2023 | 4 min read
What underlies the uneven burden of autoimmunity between the sexes has remained a mystery. Now, scientists found clues by turning to a key player on the X chromosome.
Next-Generation Sequencing: A World without Limits
The Scientist and Illumina | 5 min read
Centralized core facilities and commercial service providers specializing in NGS provide expertise and training for researchers new to the method.
A Long and Unhealthy Life?
Aparna Nathan, PhD | Sep 13, 2023 | 3 min read
A new mouse model shows that the Myc protein has complex effects on aging and cancer.
Ian Wilmut, Famed Scientist Who Led the Creation of Dolly the Sheep, Died at 79
Shelby Bradford, PhD | Sep 12, 2023 | 3 min read
Knighted in 2008, Sir Ian Wilmut revolutionized the field of cloning, stem cell research, and regenerative medicine.
Accessible Gel Imaging with a Cellphone
Analytik Jena | 1 min read
In the classroom or the laboratory, a new gel documentation system enables scientists to capture snapshots of their samples in real time.
Poor Cancer Prognosis Associated with a Transcriptional Signature
Charlene Lancaster, PhD | Sep 11, 2023 | 4 min read
Researchers connect a tumor’s leading edge transcriptional profile to poor survival outcomes across cancer types.
New Epigenetic Clocks May Confirm Extreme Age
Ida Emilie Steinmark, PhD | Sep 8, 2023 | 4 min read
How will a new version of epigenetic clocks aimed at validating the age of people older than 100 years of age balance accuracy and anonymity?
Digital PCR: The Journey to Superior Data
Bio-Rad Laboratories | 1 min read
With digital PCR (dPCR), researchers accurately and precisely quantitate nucleic acid samples.
Prime Editing Comes of Age
Ida Emilie Steinmark, PhD | Sep 8, 2023 | 9 min read
Since the technique was first published in 2019, prime editing has grown with lightning speed, alongside hopes for what it can achieve.
The Origins and Recent Promise of Nonsense Suppressor tRNAs
Ida Emilie Steinmark, PhD | Sep 8, 2023 | 4 min read
A discovery that goes back to the first studies of translation has become the topic of biotech buzz.