drug resistance

Mice with cancer whose KRAS proteins couldn’t link together had much better survival outcomes than those whose oncogenic mutant paired with wild-type KRAS.

Researchers find two new antibiotics that offer promise in the fight against drug-resistant bacteria.  

A new study finds that more than 200 human-targeted, non-antibiotic drugs inhibit the growth of bacterial species that make up part of the human microbiome.

In January, health officials began an aggressive vaccination campaign to counter the spreading disease.

The deadly fungus Cryptococcus deuterogattii harbors a genetic tweak that propels its mutation rate and allows it to rapidly develop antifungal resistance.

Fifty countries report strains of the bacteria that are resistant to last-resort antibiotics.

Lactobacillus parafarraginis metabolites hindered the growth of multiple, distantly related bacterial pathogens. 

Cancer can be as evasive and slippery as a spitball, but new immunotherapies are starting to connect.

Researchers unravel the sophisticated ways cancers evade treatments, including immunotherapies, designed to destroy them.

Cancers appear to be able to evolve resistance to many of the therapies doctors have tried.

The World Health Organization outlines critical-, high-, and medium-priority antibiotic development initiatives, calling on the public and private sectors to invest in additional R&D.

A study on microbe versus microbe battles within the human nose yields a new antibiotic.

A selection of notable quotes from the American Society for Microbiology’s annual meeting

Stuart Levy has spent a lifetime studying mechanisms of antibiotic resistance and crusading to abolish the use of antibiotics in animal feed.

Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.