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drug development

Circular clusters of <em>Staphylococcus aureus</em> drift on a blue background.
Retching Mice Reveal the Brain Circuit Behind Vomiting
Katherine Irving | Nov 2, 2022 | 2 min read
The discovery could one day lead to the development of better antinausea medications.
A vial labeled &ldquo;RSV vaccine&rdquo; on a reflective surface next to a syringe.
After Decades of Delays, RSV Vaccines Show Promise in Early Data 
Dan Robitzski | Nov 1, 2022 | 3 min read
Both Pfizer and GSK have shared preliminary data suggesting that their experimental vaccines can protect older adults and newborn infants from the virus.
Leveraging Stem Cells to Create Better Disease Models
Leveraging Stem Cells to Create Better Disease Models
The Scientist | 2 min read
Clive Svendsen, Meritxell Huch, Ameen Salahudeen, and Maksim Plikus will discuss the latest advances in using patient-derived stem cells to create more accurate disease models.
A vet and technician take a sample from a dog for use in PetDx&rsquo;s OncoK9 test, which screens cell-free DNA for genomic alterations associated with cancer.
The Pet Health Industry Takes on Canine Cancer
Diana Kwon | Oct 17, 2022 | 9 min read
Advanced genomic tools have provided biotech companies new approaches to help our furry friends—but experts say several limitations remain.
a person fumigates a red brick pathway to control mosquitoes in the fight against Dengue virus.
European Medicines Agency Recommends Approving Takeda’s Dengue Vaccine
Katherine Irving | Oct 14, 2022 | 2 min read
In clinical trials, the new inoculation demonstrated greater protection for children and people older than 45 than the existing dengue vaccine.
Sino Biological&nbsp;
CAR Technology in Cancer Therapy: From CAR-T to CAR-NK
The Scientist and Sino Biological | 4 min read
From early target discovery to preclinical development stages, researchers explore novel strategies for effective cell therapies in cancer treatment.
Man with blue shirt and tie smiling at camera.
Pharmacologist and Olympian David Bailey Dies at 77
Lisa Winter | Oct 7, 2022 | 3 min read
He was best known for his discovery that grapefruit juice makes some medications less effective or potentially dangerous.
A black and white photo of a woman in a plumed hat in a laboratory classroom with several men
Birth of The Pill, 1956–1960
Andy Carstens | Oct 3, 2022 | 2 min read
Researchers overseeing the clinical trial for the first FDA-approved oral contraceptive claimed the drug gave the Puerto Rican participants power over their family planning. Critics claimed the women were exploited.
iStock
Targeting the Undruggable
The Scientist | 1 min read
Through a combination of basic science research and clinical trials, researchers uncover innovative approaches for targeted cancer treatment. 
Illustration of light blue neurons with white amyloid plaques accumulating on their axons.
New Alzheimer’s Drug Slows Cognitive Decline in Clinical Trial
Dan Robitzski | Sep 28, 2022 | 2 min read
The Biogen-developed treatment, called lecanemab, appears to have a more clear-cut effect on slowing the disease than the company’s previous Alzheimer’s drug, Aduhelm.
A germinal center inside a lymph node
Slow Vaccine Delivery May Maximize Immune Response
Alejandra Manjarrez, PhD | Sep 23, 2022 | 5 min read
A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.
Thermo
Molecular Diagnostics: An Eye Toward the Future
The Scientist and Thermo Fisher Scientific | 2 min read
Scientists discuss their successes and challenges when creating new assays for molecular diagnostics.
Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.<br><br>
Immunotherapy Treats Fibrosis in Mice
Alejandra Manjarrez, PhD | Sep 15, 2022 | 4 min read
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
illustration of blue cells with exosomes budding off of them and floating away
Nanoparticles Spur Mouse Immune System to Attack Cancer
Shafaq Zia | Sep 13, 2022 | 2 min read
A study finds that engineered exosomes are effective in mice, but their potential use in humans raises safety questions.  
Photograph of scientists working while wearing PPE
Contract Vivarium Facilities for Preclinical Discovery
The Scientist and Mispro | 3 min read
Researchers rent contract vivarium space for greater experimental control, productivity, and reproducibility when developing new therapeutics.
woman smiling at camera
Renee Wegrzyn Tapped to Head ARPA-H
Andy Carstens | Sep 12, 2022 | 2 min read
As the new agency’s director, the DARPA veteran will spearhead a high-risk, high-reward approach to biomedical research.
A 3D rendering of a neuron
Independent FDA Advisory Panel Recommends Approving ALS Drug
Amanda Heidt | Sep 8, 2022 | 4 min read
The group’s 7-2 ruling in favor of the therapeutic represents a shift from previous deliberations, in which data on its effectiveness was deemed insufficient.
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Building Bridges for Translational Research - A Special Podcast Series
The Scientist and Cytiva | 2 min read
Translational scientists discuss their experiences taking preclinical concepts to the market.
the Melbourne skyline with lake in foreground
New Australian Center Will Develop Therapies for Future Pandemics
Shawna Williams | Aug 31, 2022 | 2 min read
Launched with a $172 million philanthropic donation and funds from the state of Victoria, the Melbourne-based research institute aims to construct drug discovery platforms to speed the introduction of new therapies.
A pregnant woman gets her blood pressure checked by a doctor
U.K. Health Authority Investigates Epilepsy Drug’s Link to Autism
Peter Hess, Spectrum | Aug 30, 2022 | 3 min read
The Medicines and Healthcare products Regulatory Agency’s investigation comes after a study showed prenatal exposure to topiramate roughly triples a child’s likelihood of having autism or intellectual disability.
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