CRISPR/Cas

A novel system for customizable DNA-hydrogel manipulations

Hundreds of CRISPR patents have been granted around the world, and the number of applications continues to grow at a rapid pace.

Researchers combine CRISPR technology with a graphene transistor to create an electronic sensor for particular DNA sequences.

A CRISPR-based electronic sensor flags target DNA sequences at high speed.

The US patent office declares an interference between the intellectual property held by the Broad Institute and several patent applications filed by the University of California—opposite its previous ruling.

Machine learning algorithms predict the repairs made to DNA after Cas9 cuts.

Double-strand breaks can produce several different outcomes.

CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.

A new study indicates that the modified CRISPR-Cas9 technology will need to be further refined before it can safely be used for research and therapeutic applications.

One person with multiple myeloma and one with sarcoma are the first so far to receive the genetically engineered T cells in the study.

In CRISPRed fruit flies that lack certain antimicrobial peptides, bacterial infections flourish, as revealed by fluorescent markers.

Adenine editing enzymes have been adapted for use in plants.

Adenine editing enzymes have been adapted for use in plants.

Researchers edited macaque embryos to induce symptoms of sleep disorders and chose one animal to clone. A bioethicist questions the study’s appropriateness.

Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.

Researchers repurpose the CRISPR machinery to turn whole classes of transposable elements on or off.

From 500-million-year-old fat to a newly discovered virus, here are some stunners from The Scientist in 2018.

He Jiankui says he has successfully used CRISPR-Cas9 to tweak the genes of twins born earlier this month. Some independent experts are dubious.

Separate proof-of-concept studies report success against two inherited diseases.