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cell signaling
Interrogating the Complexities of the Tumor Microenvironment
Alison Halliday, PhD, Technology Networks | May 19, 2023 | 5 min read
Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.
How Cells in the Skin Team Up To Fight Pathogens
Rachael Moeller Gorman | Apr 12, 2023 | 4 min read
Immune cells and pain neurons form complex partnerships to protect our bodies from pathogens, new research reveals.
Shining a Light on Mass Photometry
The Scientist and Refeyn | 3 min read
Mass photometry is an interferometric scattering-based technique offering researchers unprecedented characterization of biomolecular complexes and oligomerization in physiologically-relevant situations.
Mother’s Circadian Rhythms Mirrored in Fetal Rat Brains
Bianca Nogrady | Sep 12, 2022 | 2 min read
Before their own central clocks develop, the brains of fetal rats detect their mother’s metabolic cycle to help regulate the expression of certain genes.
Protein Mediates Non-Genetic Inheritance of Growth Strategies
Catherine Offord | Jan 4, 2022 | 2 min read
An RNA-modifying enzyme passed to daughter cells during budding allows yeast cells to switch between faster- and slower-growing phenotypes.
Exploring the World of Glycobiology
The Scientist and Vector Laboratories | 1 min read
Researchers study sugar modifications to understand health and disease.
Epithelial Cell Signaling Helps Maintain Tissue Integrity
Annie Melchor | Nov 1, 2021 | 2 min read
Using a transgenic fruit fly model, researchers demonstrate how epithelial barriers are maintained in living organisms despite high levels of cell turnover and death.
Infographic: Modeling Neurodegenerative Diseases with Yeast
Mahlon Collins | Oct 1, 2021 | 3 min read
Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.
It’s Bittersweet: The Tumorigenic Potential of Glycosylation
The Scientist Creative Services Team in collaboration with Vector Laboratories | 1 min read
Karen Abbott and Susan Bellis discuss how to detect and block tumorigenic glycosylation signatures to diagnose and treat cancer.
Bless You: Mouse Model Reveals Molecular Pathway Behind Sneezing
Amanda Heidt | Oct 1, 2021 | 3 min read
Researchers have identified specific cells and neuropeptides involved in mediating the sneeze response in mice exposed to allergens or chemical irritants such as capsaicin.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021 | 10+ min read
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
High-Throughput Solutions for Lead Candidate Discovery
The Scientist and Thermo Fisher Scientific | 1 min read
New technologies allow researchers to scale up assays for cellular functions.
Infographic: The Neural Pathway of Sneezing
Amanda Heidt | Oct 1, 2021 | 1 min read
A mouse study identifies the brain regions and specific signaling factors that regulate the sneeze response.
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021 | 10+ min read
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?
Understanding the Complexity of Cancer with Cryo-EM
The Scientist and Thermo Fisher Scientific | 1 min read
Explore how researchers use cryogenic electron microscopy (cryo-EM) to identify how mutations affect protein signaling and function through structural or conformational changes.
Newly Discovered Glycosylated RNA Is All Over Cells: Study
Christie Wilcox, PhD | May 18, 2021 | 8 min read
Prior to a 2019 preprint, “glycoRNAs” weren’t known to exist. Now, the researchers who found them say they’re on lots of cells and may play a role in immune signaling.
High Stress Hormone Levels Halt Mouse Fur Growth
Jef Akst | Apr 1, 2021 | 4 min read
Corticosterone interferes with signaling in the skin that normally activates hair follicle stem cells, possibly explaining the link between stress and hair loss.
Surveillance Gaps: How Cancer Arises
The Scientist | 1 min read
Surveillance Gaps: How Cancer Arises
New Understanding of Metastasis Could Lead to Better Treatments
Shawna Williams | Apr 1, 2021 | 10+ min read
Recent insights, such as the recognition that disseminated cancer cells can lie dormant for years before seeding secondary tumors, suggest novel strategies for fighting metastatic disease.