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3D representation of a DNA helix and with a base offset from the main helix, illustrating the concept of base editing.

A CRISPR Alternative for Correcting Mutations That Sensitize Cells to DNA Damage

Deanna MacNeil, PhD | Oct 10, 2022 | 3 min read

Researchers turned to base editors to correct mutations causing the rare genetic disease Fanconi anemia without inducing double-strand DNA breaks.

Hematopoietic Stem Cells and Their Role in Development and Disease Therapy

Jennifer Zieba, PhD | Aug 24, 2022 | 5 min read

Hematopietic stem cells (HSCs) are multipotent cells found in the blood and bone marrow with the ability to self-renew and differentiate into multiple cell types during bone marrow hematopoiesis

Infographic: Steps in Cancer Metastasis

Shawna Williams | Apr 1, 2021 | 2 min read

It’s now thought that in many cases, cancer cells disseminate from the primary tumor site early on and lie dormant for long periods rather than only venturing out from primary tumors at an advanced stage.

The MSC: Regeneration Orchestrator

The Scientist Staff | Nov 16, 2020 | 7 min read

Scientists uncover the promise of mesenchymal stem cells (MSCs), also known as medicinal signaling cells, to modulate the immune system and regenerate tissue.

Infographic: How Vaccines Train Innate Immunity

Shawna Williams | Nov 1, 2020 | 1 min read

A recent study elucidates some of the changes that occur in the body after inoculation with a tuberculosis vaccine.

Multiomic Single-Cell Analysis Identifies a Unique Stem and Progenitor Population

The Scientist | Jul 14, 2020 | 2 min read

Margaret Nakamoto will introduce the BD Rhapsody™ Single-Cell Analysis System, and Ravi Majeti will discuss how he and his team used concurrent RNA and BD® AbSeq Antibody-oligo multiplexed surface marker analysis to improve HSPC clustering and characterize specific phenotypic states along unique hematopoietic differentiation trajectories.

mice bone marrow hematopoietic stem cells

Image of the Day: Powerful Protein

Chia-Yi Hou | Apr 25, 2019 | 1 min read

An experiment tests whether a protein treatment can help hematopoietic stem cells recover after mice are exposed to radiation.

Human Skeletal Stem Cell Found

Abby Olena, PhD | Sep 20, 2018 | 3 min read

Researchers recovered the cells that give rise to bone and cartilage from fetal and adult bone marrow and also derived them from induced pluripotent stem cells.