autoimmunity

What underlies the uneven burden of autoimmunity between the sexes has remained a mystery. Now, scientists found clues by turning to a key player on the X chromosome.

By editing a mutated immune regulatory gene in patient cells, Rosa Bacchetta brings hope to those suffering from IPEX syndrome.

By editing primary T cells with CRISPR, researchers begin to settle a long-standing debate about a common autoimmunity risk variant.

A therapy for type 1 diabetes is the first to treat patients before symptoms appear, paving the way toward preventing this and other autoimmune diseases.

Staphylococcus aureus appears to be the culprit.

A new study points to repercussions of the Medieval pandemic for the health of modern humans.

Recent studies have lent support for a variety of hypotheses explaining the debilitating symptoms affecting millions of people after SARS-CoV-2 infection.  

Scientists discovered a possibly autoreactive T cell population that forecasts and supports disease progression.

Research traces the evolution of a gene variant that reduces the risk of Alzheimer’s disease, finding that it originally evolved in response to infectious bacteria.

Genetic variants that reduce the editing levels of double-stranded RNA are associated with autoimmune and immune-mediated conditions, a study finds.

Several lines of evidence suggest that targeting the body’s defense pathways might help treat a subset of people with the psychiatric disorder. But many open questions remain.

Scientists have pinpointed several pathways through which the immune system could disrupt neuronal functioning and thereby lead to psychotic symptoms.

Roseolovirus infection disrupts how the body trains immune cells not to attack it, a mouse study shows.