aging

Repairing damaged DNA appears to drive aging by causing the loss of epigenetic information, but restoring that information reverses such effects, a study finds.

Mice that received the stem cell–derived treatment were less frail compared with controls, a study reports.

Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.

Researchers say there may be similar, human genes whose effects on lifespan vary by sex.

Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests.

Researchers caution that it’s too soon to recommend supplements based on the results of a new study.

Researchers say they've figured out how some reproductive ants live up to 30 years—far longer than workers.

The Middlebury College neuroscientist explores enzymes that affect brain cell development and neurodegeneration.

Alysson R. Muotri discusses his launch of brain organoids into outer space and how microgravity enriches our understanding of brain development and disease.

Renewing the aging gut microbiome holds promise for preventing inflammatory brain and eye degeneration.

Research traces the evolution of a gene variant that reduces the risk of Alzheimer’s disease, finding that it originally evolved in response to infectious bacteria.

The cells’ mitochondria skip a key metabolic reaction that takes place in other cells in the body, a study finds.

In a citizen science project, thousands of pet dogs are helping scientists to understand what happens to memory and cognition in old age.

Two studies show negligible rates of aging in some types of turtles and other cold-blooded creatures, but that doesn’t mean they’re immortal.

Health data from 5,744 adults over the age of 50 reveals an association between stressors such as discrimination and a relatively small proportion of younger infection-fighting immune cells.

Delivering antioxidants via extracellular vesicles to atrophied muscles restores them during rehabilitation.